Identify the Cause of Your Ataxia Symptoms
One test, clear answers.
Genomic Unity® provides the most comprehensive genetic testing available.
What is ataxia?
Ataxia is a neurological disorder that affects movement, causing unsteady walking. Symptoms worsen over time, often leading to severe mobility challenges. Ataxia can also cause:
- Dizziness
- Tremors
- Difficulty speaking or swallowing
While symptoms can begin in childhood, they often first appear in adulthood.
Why genetic testing is critical
Ataxia can be caused by DNA changes in >50 different genes – including many with complex changes known as repeat expansions1.
Genetic testing is essential to confirm a diagnosis and guide treatment. Early genetic testing may:
- Inform prognosis
- Identify targeted treatments or clinical trials
- Guide family planning decisions
Genomic Unity® provides the most comprehensive testing
When it comes to genetic testing, technology matters.
Traditional testing often involves sequential tests that may miss crucial information. Genomic Unity® uses whole genome sequencing to detect DNA changes ranging in size from single base changes to large structural changes – including repeat expansions in >20 movement disorder genes – with a single test.
Our advanced technology ensures the most accurate and complete results available.
Why choose Genomic Unity®?
- One test replaces multiple sequential tests
- Covers >20 movement disorder repeat expansion genes*
- Get your results in just 4-8 weeks
- Simple insurance and self-pay options
*Including BEAN1, FGF14, FXN, RFC1, and ZFH3.
Ask your doctor about Genomic Unity® testing for ataxia
Ask your doctor about Genomic Unity® testing
Talking with your healthcare provider is the first step. Start a conversation using these questions:
- What type of genetic test is best for my symptoms?
- What genetic conditions can the test detect or miss?
- How accurate are the results?
FAQs
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Genomic Unity® is recommended if your healthcare provider suspects ataxia or another movement disorder.
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Genomic Unity® detects many types of ataxia including:
- Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS)
- Dentatorubral-pallidoluysian atrophy (DRPLA)
- Friedreich’s ataxia
- Global developmental delay, progressive ataxia, and elevated glutamine (GDPAG)
- Spinocerebellar ataxias 1, 2, 3, 4, 6, 7, 8, 10, 12, 17, 27B, 31, 36
It also detects related movement disorders including:
- Amyotrophic lateral sclerosis (ALS)
- Huntington’s disease
- Parkinson’s disease
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Genomic Unity® detects repeat expansions in the following ataxia genes: ATN1, ATXN1, ATXN2, ATXN3, ATXN7, ATXN8OS, ATXN10, BEAN1*, CACNA1A, FGF14, FMR1, FXN, GLS, NOP56, PPP2R2B, RFC1, TBP, and ZFHX3.
It also detects repeat expansions in the following related movement disorder genes: HTT, JPH3, and NOTCH2NLC.
View all repeat expansions detected by Variantyx testing.
*BEAN1 repeat expansions are only detected when Genomic Unity® 2.0 is ordered.
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A test report is sent to your doctor within 4-8 weeks of receiving your sample.
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Yes! Genomic Unity® is covered by most insurances. For cases where insurance coverage is not available, we offer self-pay options.
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Genomic Unity® testing must be ordered by a healthcare provider.
If your healthcare provider needs assistance with obtaining test order forms, sample collection kits, etc, please contact us – we’re happy to help.
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Visit the National Ataxia Foundation for more resources about diagnosis, treatment, and support.
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References
Ready to learn more?
Connect with a Clinical Specialist to discuss Genomic Unity® testing. We’re here to help you understand your options.