Reproductive Genetics

We are setting the standard in reproductive genetics

At Variantyx, we are setting the standard of genome analysis. We are leading the way by offering the most comprehensive diagnostic testing clinically available for prenatal analysis or pregnancy loss. With thorough interrogation of the genome, we have the ability to detect all major clinically relevant variant types from one sample. A single, unified clinical report is generated through phenotype-driven variant evaluation performed by clinical experts.

Using our methodology’s superior analytical and clinical validity, we are providing better overall performance, diagnostic yield and speed of diagnosis. All at lower overall cost.

Our methodology preserves genomic data

Amniocentesis/CVS/POC are critical medical procedures used to collect fetal DNA for the purpose of analyzing the genetic material of an unborn child. Such testing helps identify potential genetic conditions or abnormalities that could impact the child’s health. However, the testing method chosen is paramount to ensuring that you receive the most accurate and comprehensive information.

While traditional methods such as PCR-based panels or exome sequencing have been widely used, they have limitations that can affect the accuracy and comprehensiveness of results. These tests typically focus on a small portion of the genome and can remove or skew data, leading to fragmented coverage of only 1-2% of the patient’s DNA. This means key genetic variants may be missed, leaving potential risks undetected.

Whole genome sequencing (WGS) offers a more advanced approach, generating comprehensive uniform coverage of over 98% of the patient’s DNA. By utilizing advanced genomic technology, you can provide your patients with the most informed, reliable insights into their pregnancy and the health of their unborn child.

Our reproductive analysis portfolio

IriSight® CNV Analysis

A direct replacement to CMA, this test detects aneuploidies, micro deletions/duplications, large and small CNVs, inversions, unbalanced translocations, aneuploidies, LOH and UPD. All with a single amniotic or CVS sample.

IriSight® Comprehensive Analysis – Prenatal

This test considers the entire genome, identifying all relevant types of DNA changes for the most comprehensive view possible.

Flexible reflex options facilitate first-line testing

First-line testing with Genomic Unity® is the fastest way to reach a clear diagnostic outcome.

Every test is performed on our whole genome platform. Available automatic reflex options enable starting with targeted, insurance-covered testing followed by a full, comprehensive analysis in the event the first test is non-diagnostic.

Learn more about our billing options.